ACHAIKI IATRIKI | 2025; 44(4): 174
Letter from the editor
Dear colleagues,
In the current issue, the editorial by Mastorogianni et al. summarizes the emerging therapeutic strategies for celiac disease that go beyond the traditional gluten-free diet, emphasizing novel pharmacological and immunological approaches targeting various aspects of disease pathophysiology. The editorial by Efthymiou et al. highlights the current role of colistin in the management of multidrug-resistant Gram-negative infections, focusing on its pharmacologic profile, resistance trends, clinical applications, and place in therapy amid emerging treatment options.
The current issue features three review articles. The first, authored by Efthymiou et al., provides an overview of the diverse causes and histopathologic patterns of granulomatous lymphadenopathy, emphasizing its diagnostic significance and clinical relevance as a histologic finding that can guide the identification of underlying infectious and non-infectious diseases. The review by Papasotiriou et al. presents contemporary data on the safety and risk of developing of acute kidney injury after the administration of iodinated contrast agents, as well as the risk of developing nephrogenic systemic fibrosis after exposure to gadolinium-based contrast media. Finally, the review by Tsoupra S. outlines the current understanding, diagnostic strategies, and management principles for elevated aminotransferases, highlighting their clinical significance and the importance of a structured approach to identifying underlying hepatic and extrahepatic causes.
Lastly, this issue features a case report by Bousis et al., which discusses the complications of invasive meningococcal disease, their management, and their impact on the overall prognosis of individuals with meningococcal sepsis.
Yours sincerely,
C Triantos
Associate Professor in Internal Medicine
and Gastroenterology Faculty of Medicine,
School of Health Sciences, University of Patras
Editor-in-Chief of the journal “ACHAIKI IATRIKI”